SCIENCE BEHIND BIO BALANCE PROBIOTICS
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“Probiotics are necessary for the daily prevention of premature aging due to environmental aggressors like air pollution, UV radiation, smoke, and stress. I highly recommend Bio Balance Probiotics skincare range as one of the essential parts of everyone’s daily skincare routine.”

Pharmacist Kenan Alpay

01/

HOW WE AGE?

During a lifetime, skin will change in appearance and structure not only because of chronological and intrinsic processes but also due to several external factors such as gravity, sun and ultraviolet exposure, and high levels of pollution; or lifestyle factors that have important and obvious effects on skin aging, such as diet, tobacco, illness, or stress.

02/

BIOLOGICAL AGING

With time, we all get visible lines and wrinkles on our face.
It is natural and it is controlled by our genes.
The medical term for this type of aging is biological aging.
However studies show that our skin ages faster than our biological aging.

EXTERNAL / PREMATURE AGING

UV rays account for 80% of external skin ageing.
Sun, pollution, smoke, alcohol, stress, our environment and lifestyle choices can cause our skin to age before its time.
Fine lines, wrinkles, brown spots develop.
Skin gets drier, thinner and more sensitive.

03/

IS AGING PREVENTABLE AND REVERSIBLE PROCESS?

Good news is premature aging can be reversed and prevented by applying the right skin care and taking preventive actions.

04/

SLOW SIGNS OF AGING WITH OUR PROBIOTIC ENZYMES POWERED FORMULA

LACTOBACILLUS & BIFIDA FERMENT LYSATE
Probiotics are microorganisms that deliver health benefits when consumed or applied topically on the skin.

1. Lactobacillus: Strains of Lactobacillus casei and Lactobacillus acidophilus, freeze-dried.

2. Bifida Ferment is a probiotic bifidobacteria disintegrated in a bioactive milk-based nutrient.

05/

UNIQUE FEATURES OF BIO BALANCE PROBIOTICS

  • CONTROLS EXTERNAL AGING
  • CONTROLS BIOLOGICAL WRINKLE
  • SENSORY NEUROMODULATOR RELAXANT
  • CELL DETOXIFICATION

06/

WHY WE NEED PROBIOTICS?

  • Slows down external skin aging
  • Protect skin collagen & elastin
  • Strengthen skins immune system, makes the skin more stress-resistant
  • Act as a protective shield for the skin, protects it from environmental damagers
  • Reduce skin irritation
  • Nourishes and soothes skin naturally

07/

After three years of in-depth research, we incorporated all goodness of probiotic bacteria Lactobacillus and Bifida Ferment into Bio Balance Probiotics range, which prevents and corrects the damage caused by environmental exposure.

SCIENTIFIC DATA
IN-VITRO STUDIES

SYNTHESIS OF 6 MAJOR CONSTITUENTS OF THE SKIN

Collagen I - Immunolabelling
In Vitro
2% MATRIXYL® synthe6™
Production
On fibroblasts
+105%, p < 0.01
Ex Vivo
2% MATRIXYL® synthe6™
Production
On skin explants
+37.5%, p < 0.01

Twice daily application for 5 days.

Control
2% MATRIXYL® synthe6™
Control
2% MATRIXYL® synthe6™
Collagen III- Immunolabelling
2% MATRIXYL® synthe6™
Production
On fibroblasts
+104%, p < 0.01
Collagen IV- ELISA Method
On fibroblasts
+42%, p < 0.01
HSP47- Western Blot
On fibroblasts
+123%, p < 0.01

The chaperone protein HSP47 is necessary for the maturation and stabilization of collagens I to V.

Control

MATRIXYL® synthe6™ stimulates the synthesis of collagen types I, III and IV. HSP47 confers maturation and stabilisation to the fibres.

2% MATRIXYL® synthe6™
IN-VIVO STUDIES

In-Vivo Study of active ingredient 2% Matrixyl Synthe6.

LIFTING OF THE SAGGING NECK SKIN

Sagging surface (n=31, after 3 weeks)
-10.6%, p < 0.01 vs T0 up to -56%

In only 3 weeks, Majestem™ tightens the sagging neck skin to sculpt and restore a youthful neck line.

Smoothing of folds (evaluation by 7 expert judges, n=28, after 6 weeks)

After 6 weeks, the expert judges have noticed a long-term efficacy associated with a visible smoothing of neck folds.

In-Vivo Study of active ingredient 2% Majestem™


LIFTING OF THE UPPER PART OF THE CHEEK

Circumference
-9%, p < 0.01 vs T0 up to -33%
Volume
-8.8%, p=0.08 vs T0 up to -84%

Fringe projection on volunteers with tear trough (n=21, after 6 weeks) Tear trough: hollow running from the nose and under the eyes.

Majestem™ enhances the cheeks contour by reducing the tear trough.


SMOOTHING OF THE CROWS FEET WRINKLES

Wrinkle surface

-10.7%, p < 0.05 up to -16.8%*,
p < 0.05 vs T0
Wrinkle depth

-6.2%, p < 0.05 up to -10%*,
p < 0.01 vs T0
Roughness

-5.7%, p < 0.05 up to -9.1%*,
p < 0.01 vs T0

*panel with photodamaged skin (n=19)

Majestem™ smoothes out wrinkles with even greater efficiency on photodamaged skin.